Global warming and nanoplastic toxicity; small temperature increases can make gill and liver toxicity more dramatic, which affects fillet quality caused by polystyrene nanoplastics in the adult zebrafish model

• Published in: The Science of the total environment 2023-09, Vol.892, p.164682-164682, Article 164682
• Main Authors: Şenol, Onur, Sulukan, Ekrem, Baran, Alper, Bolat, İsmail, Toraman, Emine, Alak, Gonca, Yildirim, Serkan, Bilgin, Gökhan, Ceyhun, Saltuk Buğrahan
• Format: Article
• Language: English
• Subjects: adhesion; adults; Animals; climate change; Danio rerio; DNA damage; environment; epithelium; fillet quality; Gills - metabolism; Global Warming; hepatotoxicity; hyperemia; inflammation; lipid peroxidation; Lipids; liver; Liver - metabolism; Metabolomics; Microplastics - metabolism; Microplastics - toxicity; muscles; Nanoparticles - toxicity; Nanoplastic; nanoplastics; necrosis; Plastic toxicity; pollution; Polystyrene; polystyrenes; Polystyrenes - metabolism; Polystyrenes - toxicity; Temperature; Water Pollutants, Chemical - metabolism; Water Pollutants, Chemical - toxicity; Zebrafish - physiology
• ISSN: 0048-9697; 1879-1026
• DOI: 10.1016/j.scitotenv.2023.164682

Increasing nanoplastics (NPs) pollution may lead to unknown environmental risks when considered together with climate change, which has the potential to become an increasingly important environmental issue in the coming decades. In this context, the present study aimed to evaluate the stressor modelling of polystyrene nanoplastic (PS-NPs) combined with temperature increase in zebrafish. For this purpose, changes in gill, liver and muscle tissues of zebrafish exposed to PS-NPs (25 ppm) and/or different temperatures (28, 29 and 30 °C) for 96 h under static conditions were evaluated. The results obtained emphasize that exposure to PS-NPs stressors under controlled conditions with temperature increase induces DNA damage through stress-induced responses accompanied by degeneration, necrosis and hyperaemia in zebrafish liver and adhesion of lamellae, desquamation and inflammation in lamellar epithelium in gills. Metabolomic analyses also supported changes indicating protein and lipid oxidation, especially PS-NPs-mediated. These findings will contribute to the literature as key data on the effects of PS-NPs presence on protein/lipid oxidation and fillet quality in muscle tissues. [Display omitted] •The toxicity of PS increased with the increase in temperature in zebrafish.•Temperature increases of 1 degree causes the severity of PS-induced damage to gills and liver.•Significant density differences were detected in many metabolites.