Contemporary Adjuncts to Hemorrhage Control

Trauma remains the most common cause of death among people 1 to 45 years of age, with hemorrhage being the most common cause of preventable death. For patients with hemorrhagic shock, expeditious control of bleeding is required to maximize chances for survival. Hemostasis requires that patients have...

Full description

Saved in:
Bibliographic Details
Published in:JAMA : the journal of the American Medical Association 2023-11, Vol.330 (19), p.1849-1851
Main Authors: Tisherman, Samuel A., Brenner, Megan L.
Format: Article
Language:English
Subjects:
Aorta
Balloon treatment
Bleeding
Cardiovascular system
Clinical trials
Coagulation
Hemodynamics
Hemorrhage
Hemostasis
Hemostatics
Occlusion
Preventable deaths
Trauma
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Trauma remains the most common cause of death among people 1 to 45 years of age, with hemorrhage being the most common cause of preventable death. For patients with hemorrhagic shock, expeditious control of bleeding is required to maximize chances for survival. Hemostasis requires that patients have sufficient functioning of the coagulation system, and, in most cases, expeditious interventions (open surgical or endovascular) aimed at controlling the hemorrhage. This issue of JAMA includes 2 randomized clinical trials of interventions aimed at achieving rapid hemostasis, both carried out in many of the same institutions. Davenport et al studied early, empirical, high-dose cryoprecipitate to correct hypofibrinogenemia that is often found in trauma patients. Jansen et al studied the use of resuscitative endovascular balloon occlusion of the aorta (REBOA) to decrease bleeding and improve hemodynamics until procedures to achieve definitive hemostasis were performed.
ISSN:0098-7484
1538-3598
DOI:10.1001/jama.2023.16135