Targeting neuromuscular junction to treat neuromuscular disorders

The integrity and preservation of the neuromuscular junction (NMJ), the interface between the motor neuron and skeletal muscle, is critical for maintaining a healthy skeletal muscle. The structural and/or functional defects in the three cellular components of NMJ, namely the pre-synaptic terminal, s...

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Bibliographic Details
Published in:Life sciences (1973) 2023-11, Vol.333, p.122186, Article 122186
Main Author: Qaisar, Rizwan
Format: Article
Language:English
Subjects:
Chronic obstructive pulmonary disease
humans
mice
motor neurons
Muscle wasting
muscles
Neuromuscular junction
skeletal muscle
synapse
therapeutics
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