Lower urinary tract symptoms in patients with inflammatory bowel diseases: A cross-sectional observational study

• Published in: Digestive and liver disease 2024-04, Vol.56 (4), p.628-634
• Main Authors: Romano, Lorenzo, Pellegrino, Raffaele, Arcaniolo, Davide, Gravina, Antonietta Gerarda, Miranda, Agnese, Priadko, Kateryna, De Gennaro, Nicola, Santonastaso, Antonio, Palladino, Giovanna, Crocetto, Felice, Barone, Biagio, Cuomo, Antonio, Facchiano, Angela, Mucherino, Caterina, Spirito, Lorenzo, Sciorio, Carmine, de Sio, Marco, Romano, Marco, Napolitano, Luigi
• Format: Article
• Language: English
• Subjects: BFLUTS; Colitis, Ulcerative - complications; Colitis, Ulcerative - epidemiology; Crohn Disease - complications; Crohn Disease - epidemiology; Female; Humans; Inflammatory bowel disease; Inflammatory Bowel Diseases - complications; Inflammatory Bowel Diseases - epidemiology; IPSS; Lower Urinary Tract Symptoms - diagnosis; Lower Urinary Tract Symptoms - epidemiology; Male; NIH-CPSI; Prostatitis - complications; Prostatitis - epidemiology; Quality of Life
• ISSN: 1590-8658; 1878-3562
• DOI: 10.1016/j.dld.2023.10.010

Inflammatory Bowel Diseases (IBD), Crohn's Disease (CD), and Ulcerative Colitis (UC) may have extraintestinal manifestations, including disorders of the urinary tract. The prevalence of lower urinary tract symptoms (LUTS) in IBD patients remains unclear. Assess the prevalence of LUTS in patients with CD or UC, evaluate the variables implicated in any difference in LUTS prevalence between CD or UC, and assess any relationship between disease activity and LUTS LUTS were evaluated in 301 IBD patients through standardised questionnaires: Bristol Female Lower Urinary Tract Symptoms (BFLUTS), NIH-Chronic Prostatitis Symptom Index (NIH-CPSI), and International Prostate Symptom Score (IPSS). IBD activity was determined through the Crohn's Disease Activity Index (CDAI), Partial Mayo Score (PMS), and Total Mayo Score (TMS). BFLUTS total score for females was 6 (3–11). Patients with a higher age at diagnosis had worse filling symptoms (p = 0.049) and a worse quality of life (p = 0.005). In males, 67.1% had mild, 28.5% moderate, and 4.4% severe IPSS symptom grades. The overall NIHCPSI prevalence of chronic prostatitis-like symptoms was 26.8%. The questionnaires revealed some significant differences in the subgroups analysed. LUTS should be evaluated in IBD patients by urologic-validated questionnaires for prompt diagnosis and early treatment.