Developmental, cytogenetic and epigenetic consequences of removing complex proteins and adding melatonin during in vitro maturation of bovine oocytes

maturation (IVM) of germinal vesicle intact oocytes prior to fertilization (IVF) is practiced widely in animals. In human assisted reproduction it is generally reserved for fertility preservation or where ovarian stimulation is contraindicated. Standard practice incorporates complex proteins (CP), i...

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Bibliographic Details
Published in:Frontiers in endocrinology (Lausanne) 2023, Vol.14, p.1280847
Main Authors: Tutt, Desmond A. R., Guven-Ates, Gizem, Kwong, Wing Yee, Simmons, Rob, Sang, Fei, Silvestri, Giuseppe, Canedo-Ribeiro, Carla, Handyside, Alan H., Labrecque, Remi, Sirard, Marc-André, Emes, Richard D., Griffin, Darren K., Sinclair, Kevin D.
Format: Article
Language:English
Subjects:
aneuploidy
Animals
Cattle
Cytogenetic Analysis
DNA methylation
Epigenesis, Genetic
Female
Humans
In Vitro Oocyte Maturation Techniques
IVM
Lipids
melatonin
Melatonin - metabolism
Melatonin - pharmacology
oocyte
Oocytes - metabolism
serum
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