Persistant Left Superior Vena Cava with and Without Right Superior Vena Cava: Significance of Prenatal Diagnosis

This study aims to define the associated anomalies with PLSVC, and to compare single PLSVC and bilateral superior vena cava in terms of accompanying anomalies and pregnancy outcomes. This was a retrospective study of the fetuses diagnosed with single and/or bilateral SVC at a tertiary fetal medicine...

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Bibliographic Details
Published in:Pediatric cardiology 2024-02, Vol.45 (2), p.377-384
Main Authors: Kahramanoglu, Ozge, Demirci, Oya, Uygur, Lutfiye, Erol, Nurdan, Schiattarella, Antonio, Rapisarda, Agnese Maria Chiara
Format: Article
Language:English
Subjects:
Analysis
Cardiac Surgery
Cardiology
Health aspects
Medicine
Medicine & Public Health
Pregnancy
Pregnant women
Vascular Surgery
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Summary:This study aims to define the associated anomalies with PLSVC, and to compare single PLSVC and bilateral superior vena cava in terms of accompanying anomalies and pregnancy outcomes. This was a retrospective study of the fetuses diagnosed with single and/or bilateral SVC at a tertiary fetal medicine center during 8 years. We detected 16 cases of single PLSVC and 84 cases of bilateral SVC. We found an association between the PLSVC and cardiac and extracardiac anomalies. Comparison between single PLSVC and BSVC cases revealed significant differences in the occurrence of heterotaxy and right isomerism. The study highlights the importance of prenatal diagnosis in PLSVC cases. Isolated PLSVC with situs solitus may be considered a benign finding, but larger studies are needed to understand the clinical implications of PLSVC in relation to chromosomal anomalies. Routine screening protocols should include three-vessel and trachea views to detect PLSVC.
ISSN:0172-0643
1432-1971
DOI:10.1007/s00246-023-03353-0