Reward anticipation-related neural activation following cued reinforcement in adults with psychotic psychopathology and biological relatives

Schizophrenia is associated with hypoactivation of reward sensitive brain areas during reward anticipation. However, it is unclear whether these neural functions are similarly impaired in other disorders with psychotic symptomatology or individuals with genetic liability for psychosis. If abnormalit...

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Bibliographic Details
Published in:	Psychological medicine 2024-05, Vol.54 (7), p.1441-1451
Main Authors:	Demro, Caroline, Lahud, Elijah, Burton, Philip C., Purcell, John R., Simon, Joe J., Sponheim, Scott R.
Format:	Article
Language:	English
Subjects:	Adult Adults Anticipation, Psychological - physiology Bipolar disorder Brain Brain - diagnostic imaging Cortex (insular) Cues Disorders Expectations Frontal gyrus Functional connectivity Functional magnetic resonance imaging Genetics Humans Liability Magnetic Resonance Imaging Mental disorders Motivation Neostriatum Neural networks Nucleus accumbens Pleasure Psychopathology Psychosis Psychotic Disorders - diagnostic imaging Putamen Regions Reinforcement Reward Rewards Salience Schizophrenia Schizophrenia - diagnostic imaging Task performance
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