Vitamin K Status and All-Cause Mortality: Is there a link?

Mortality associated with vitamin K deficiency is the consequence of a rare, yet well-documented bleeding disorder among infants ≤8 wk of age [ [1] ]. Vitamin K deficiency bleeding (VKDB) in early infancy is secondary to insufficient vitamin K stores at birth, low vitamin K intake, and/or absorption...

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Bibliographic Details
Published in:The Journal of nutrition 2024-03, Vol.154 (3), p.799-800
Main Authors: Shea, M. Kyla, Booth, Sarah L
Format: Article
Language:English
Subjects:
Babies
Bleeding
Blood coagulation
Carboxylation
Clotting
Hemorrhage
Mortality
Phylloquinone
Prophylaxis
Risk Factors
Vitamin deficiency
Vitamin K
Vitamin K 1
Vitamins
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Summary:Mortality associated with vitamin K deficiency is the consequence of a rare, yet well-documented bleeding disorder among infants ≤8 wk of age [ [1] ]. Vitamin K deficiency bleeding (VKDB) in early infancy is secondary to insufficient vitamin K stores at birth, low vitamin K intake, and/or absorption. The resultant vitamin K deficiency reduces its ability to function as an enzyme cofactor in the carboxylation of certain vitamin K-dependent proteins involved in blood clotting. Fortunately, VKDB is mostly preventable through vitamin K prophylaxis and/or parenteral vitamin K, depending on the cause and timing of onset of VKDB [ [1] ].
ISSN:0022-3166
1541-6100
1541-6100
DOI:10.1016/j.tjnut.2024.01.014