Alactic base excess (ABE): a novel internal milieu parameter—its concept and clinical importance

Inspired by the Stewart-Figge acid–base approach, Gattinoni et al. recently introduced a new internal milieu parameter known as alactic base excess (ABE). The authors defined ABE as the sum of lactate and standard base excess. In the context of sepsis, ABE has been proposed as a valuable marker to d...

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Published in:International urology and nephrology 2024-06, Vol.56 (6), p.1983-1986
Main Authors: Hoque, Md, Nagourney, Jason, Pawlowski, Thomas, Cantos, Joaquin, Aroca-Martinez, Gustavo, Huespe, Ivan, Musso, Carlos G.
Format: Article
Language:English
Subjects:
Acidosis
Lactic acid
Medicine
Medicine & Public Health
Metabolic acidosis
Nephrology
Nephrology - Review
Patients
Renal failure
Renal function
Sepsis
Urology
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container_end_page 1986
container_issue 6
container_start_page 1983
container_title International urology and nephrology
container_volume 56
creator Hoque, Md
Nagourney, Jason
Pawlowski, Thomas
Cantos, Joaquin
Aroca-Martinez, Gustavo
Huespe, Ivan
Musso, Carlos G.
description Inspired by the Stewart-Figge acid–base approach, Gattinoni et al. recently introduced a new internal milieu parameter known as alactic base excess (ABE). The authors defined ABE as the sum of lactate and standard base excess. In the context of sepsis, ABE has been proposed as a valuable marker to discern between metabolic acidosis resulting from the accumulation of lactate and the retention of fixed acids, which can occur in cases of renal failure. Multiple studies have demonstrated that a negative ABE value (
doi_str_mv 10.1007/s11255-024-03949-2
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subjects Acidosis
Lactic acid
Medicine
Medicine & Public Health
Metabolic acidosis
Nephrology
Nephrology - Review
Patients
Renal failure
Renal function
Sepsis
Urology
title Alactic base excess (ABE): a novel internal milieu parameter—its concept and clinical importance
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