The association between mechanical CPR and outcomes from in-hospital cardiac arrest: An observational cohort study

•In this observational study of one of the largest in-hospital cardiac arrest databases we found that mechanical CPR was associated with decreased probability of survival to hospital discharge compared to manual CPR.•We found that mechanical CPR was associated with decreased likelihood of ROSC compa...

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Bibliographic Details
Published in:Resuscitation 2024-05, Vol.198, p.110142, Article 110142
Main Authors: Crowley, Conor, Salciccioli, Justin, Wang, Wei, Tamura, Tomoyoshi, Kim, Edy Y., Moskowitz, Ari
Format: Article
Language:English
Subjects:
Aged
Cardiopulmonary resuscitation
Cardiopulmonary Resuscitation - methods
Cardiopulmonary Resuscitation - statistics & numerical data
Cohort Studies
Female
Heart arrest
Heart Arrest - mortality
Heart Arrest - therapy
Humans
In-hospital cardiac arrest
Male
Mechanical CPR
Middle Aged
Patient Discharge - statistics & numerical data
Propensity Score
United States - epidemiology
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Summary:•In this observational study of one of the largest in-hospital cardiac arrest databases we found that mechanical CPR was associated with decreased probability of survival to hospital discharge compared to manual CPR.•We found that mechanical CPR was associated with decreased likelihood of ROSC compared to manual CPR only. We sought to investigate the relationship between mechanical cardiopulmonary resuscitation (CPR) during in-hospital cardiac arrest and survival to hospital discharge. Utilizing the prospectively collected American Heart Association’s Get With The Guidelines database, we performed an observational study. Data from 153 institutions across the United States were reviewed with a total of 351,125 patients suffering cardiac arrest between 2011 and 2019 were screened. After excluding patients with cardiac arrests lasting less than 5 minutes, and patients who had incomplete data, a total of 111,143 patients were included. Our primary exposure was mechanical vs. manual CPR, and the primary outcome was survival to hospital discharge. Multivariate logistic regression models and propensity weighted analyses were used. 11.8% of patients who received mechanical CPR survived to hospital discharge versus 16.9% in the manual CPR group. Patients who received mechanical CPR had a lower probability of survival to discharge compared to patients who received manual CPR (OR 0.66 95% CI 0.58–0.75; p 
ISSN:0300-9572
1873-1570
1873-1570
DOI:10.1016/j.resuscitation.2024.110142