Body composition, pulmonary function tests, exercise capacity, and quality of life in chronic obstructive pulmonary disease patients with obesity

Larger proportions of chronic obstructive pulmonary disease (COPD) patients are currently overweight or with obesity than underweight, and the combination of COPD and obesity is increasing. The purpose of this study was to investigate differences in the body composition, pulmonary function tests, ex...

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Bibliographic Details
Published in:Postgraduate medical journal 2024-06, Vol.100 (1185), p.469-474
Main Authors: Muršić, Davorka, Glunčić, Tajana Jalušić, Ostojić, Jelena, Škrinjarić-Cincar, Sanda, Kardum, Ljiljana Bulat, Dokoza, Martina, Lazarušić, Nataša Karamarković, Bešić, Erim, Samaržija, Miroslav, Dugac, Andrea Vukić
Format: Article
Language:English
Subjects:
Aged
Body Composition
Body Mass Index
Dyspnea - etiology
Dyspnea - physiopathology
Exercise Tolerance - physiology
Female
Humans
Male
Middle Aged
Obesity - complications
Obesity - physiopathology
Obesity - psychology
Pulmonary Disease, Chronic Obstructive - complications
Pulmonary Disease, Chronic Obstructive - physiopathology
Pulmonary Disease, Chronic Obstructive - psychology
Quality of Life
Respiratory Function Tests
Walk Test
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Summary:Larger proportions of chronic obstructive pulmonary disease (COPD) patients are currently overweight or with obesity than underweight, and the combination of COPD and obesity is increasing. The purpose of this study was to investigate differences in the body composition, pulmonary function tests, exercise capacity, and health-related quality of life among normal weight, overweight, and obese patients with COPD. A total of 514 patients with COPD were included in the study. According to the World Health Organization criteria for body mass index, the patients were classified as normal weight, overweight, and obese. Evaluations included fat-free mass, fat-free mass index, phase angle, pulmonary function tests, and 6-minute walk test. Dyspnea was assessed using the modified Medical Research Council dyspnea scale, and the health-related quality of life was evaluated using COPD Assessment Test and St. George's Respiratory Questionnaire. Values were compared among the three groups. There were 315 male and 199 female patients, with a mean age of 66.7 ± 8.4 years. Fat-free mass, fat-free mass index, and phase angle values were significantly higher in COPD patients with obesity than in other patients (P 
ISSN:0032-5473
1469-0756
1469-0756
DOI:10.1093/postmj/qgae024