Virucidal activity of a plant-oil-based oral rinse against respiratory viruses

Respiratory viruses have been reported to infect the salivary glands and the throat, which are potential reservoirs for virus replication and transmission. Therefore, strategies to reduce the amount of infective virus particles in the oral mucous membranes could lower the risk of transmission. The v...

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Bibliographic Details
Published in:The Journal of hospital infection 2024-05, Vol.147, p.83-86
Main Authors: Meister, T.L., Brüggemann, Y., Becker, B., Paulmann, D., Brill, F.H.H., Steinmann, E.
Format: Article
Language:English
Subjects:
Antiviral Agents - pharmacology
COVID-19 - prevention & control
EN 14476
Humans
Influenza virus
Mouthwashes - pharmacology
Oral rinse
Plant oils
Plant Oils - pharmacology
Quantitative suspension test
Respiratory Syncytial Viruses - drug effects
SARS-CoV-2 - drug effects
SARS-CoV-2, RSV
Virus Inactivation - drug effects
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Summary:Respiratory viruses have been reported to infect the salivary glands and the throat, which are potential reservoirs for virus replication and transmission. Therefore, strategies to reduce the amount of infective virus particles in the oral mucous membranes could lower the risk of transmission. The viral inactivation capacity of a plant-oil-based oral rinse (Salviathymol®) was evaluated in comparison with chlorhexidine (Chlorhexamed® FORTE) using a quantitative suspension test according to EN 14476. Salviathymol efficiently inactivated severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), respiratory syncytial virus (RSV) and two influenza strains to undetectable levels. Salviathymol has potential as preventive measure to lower transmission of respiratory viruses.
ISSN:0195-6701
1532-2939
DOI:10.1016/j.jhin.2024.02.023