Lymphopoietic cancer and other major causes of death among petrochemical researchers: an update

This study updates lymphopoietic cancer (LHC) mortality statistics and other major causes of death through 1992 for 13,188 petrochemical researchers employed between 1964 and 1986. Significant deficits of deaths were observed for all causes, all cancers, ischaemic heart disease and all external caus...

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Bibliographic Details
Published in:Occupational medicine (Oxford) 1999-02, Vol.49 (2), p.71-77
Main Authors: Lewis, R. J., Yarborough, C. M., Nicolich, M. J., Friedlander, B. R.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Chemical Industry - statistics & numerical data
Cohort Studies
Female
Hematologic and hematopoietic diseases
Hematologic Neoplasms - chemically induced
Hematologic Neoplasms - mortality
Humans
Laboratory workers
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
lymphopoietic cancer
Male
Medical sciences
mortality
Neoplasms - chemically induced
Neoplasms - mortality
New Jersey - epidemiology
Occupational Diseases - chemically induced
Occupational Diseases - mortality
occupational epidemiology
petrochemical researchers
Poisson Distribution
Research Personnel - statistics & numerical data
Sex Distribution
Survival Rate
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Summary:This study updates lymphopoietic cancer (LHC) mortality statistics and other major causes of death through 1992 for 13,188 petrochemical researchers employed between 1964 and 1986. Significant deficits of deaths were observed for all causes, all cancers, ischaemic heart disease and all external causes. The subcategory of ‘all other LHC’ was elevated among males in an exposure class containing scientists and engineers. This finding was statistically significant based on national but not state comparison rates. Poisson regression analyses showed that increasing exposure classes were not associated with LHC, but a relationship was noted for total years worked. A non-significant increase in breast cancer among females was also observed but was concentrated among the lowest exposure class. This study and other similar investigations suggest various subcategories of LHC deaths are marginally elevated among chemical researchers and engineers. Evidence for a work-related LHC hazard for this population, however, has not been identified.
ISSN:0962-7480
1471-8405
DOI:10.1093/occmed/49.2.71