Calcium-phosphate derived from mineralized algae for bone tissue engineering applications

In this work, several routes are described towards obtaining pure inorganic phases derived from Coralline officinallis red algae. The scanning electron microscopy studies have shown that it becomes possible not only to eliminate the undesired organic phase, but also to preserve or tailor the red alg...

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Bibliographic Details
Published in:Materials letters 2007-06, Vol.61 (16), p.3495-3499
Main Authors: Oliveira, Joaquim M., Grech, Jessica M.R., Leonor, Isabel B., Mano, João F., Reis, Rui L.
Format: Article
Language:English
Subjects:
Bone tissue engineering
Calcium-phosphate
Coralline officinallis
Hydroxyapatite
Mineralized red algae
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Summary:In this work, several routes are described towards obtaining pure inorganic phases derived from Coralline officinallis red algae. The scanning electron microscopy studies have shown that it becomes possible not only to eliminate the undesired organic phase, but also to preserve or tailor the red algae typical microporosity. X-ray diffraction analysis was used to investigate the phase content of the red algae before and after performing the different treatment routes. Hydroxyapatite nanocrystallites were obtained after converting the coralline calcium carbonate skeleton by means of combining thermal and chemical routes. These results were confirmed by Fourier transform infra-red spectroscopic analysis. The processing routes herein described are very promising in order to design bioceramics of algae origin that might find useful applications as bone fillers and tissue engineering scaffolds.
ISSN:0167-577X
1873-4979
DOI:10.1016/j.matlet.2006.11.099