Early-onset vs late-onset preeclampsia and risk of coronary atherosclerosis later in life: a clinical follow-up study

[Display omitted] Younger women with previous preeclampsia have an increased risk of coronary atherosclerosis. It is unknown if this risk is associated with the time of onset of preeclampsia. This study aimed to investigate if women with early-onset preeclampsia have a higher risk of coronary athero...

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Published in:American journal of obstetrics & gynecology MFM 2024-05, Vol.6 (5), p.101371, Article 101371
Main Authors: Hauge, Maria G., Linde, Jesper J., Kofoed, Klaus F., Ersbøll, Anne S., Johansen, Marianne, Sigvardsen, Per E., Fuchs, Andreas, Mikkelsen, Anders P., Gustafsson, Finn, Damm, Peter
Format: Article
Language:English
Subjects:
angiography
atherosclerosis
cardiac computed tomography
cardiovascular disease
early-onset preeclampsia
late-onset preeclampsia
preeclampsia
women
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Summary:[Display omitted] Younger women with previous preeclampsia have an increased risk of coronary atherosclerosis. It is unknown if this risk is associated with the time of onset of preeclampsia. This study aimed to investigate if women with early-onset preeclampsia have a higher risk of coronary atherosclerosis compared with women with late-onset preeclampsia, independent of other perinatal risk factors. A total of 911 women with previous preeclampsia aged 35 to 55 years participated in a clinical follow-up study, including clinical examination, comprehensive questionnaires, and cardiac computed tomography scan 13 years (range, 0–28) after index pregnancy. Early- and late-onset preeclampsia were defined as gestational age at delivery of
ISSN:2589-9333
2589-9333
DOI:10.1016/j.ajogmf.2024.101371