What is the optimum post treatment surveillance imaging protocol for low-grade appendiceal mucinous neoplasms and pseudomyxoma peritoneii?

• Published in: British journal of radiology 2024-08, Vol.97 (1160), p.1405-1412
• Main Authors: Dempsey, Philip J, Power, Jack W, Yates, Andrew H, Martín-Román, Lorena, Aird, John J, Mulsow, Jürgen, Fenlon, Helen M, Cronin, Carmel G
• Format: Article
• Language: English
• Subjects: Adenocarcinoma, Mucinous - diagnostic imaging; Adenocarcinoma, Mucinous - pathology; Adenocarcinoma, Mucinous - therapy; Appendectomy; Appendiceal Neoplasms - diagnostic imaging; Appendiceal Neoplasms - pathology; Appendiceal Neoplasms - therapy; Cytoreduction Surgical Procedures - methods; Humans; Hyperthermic Intraperitoneal Chemotherapy; Magnetic Resonance Imaging - methods; Neoplasm Grading; Neoplasm Recurrence, Local - diagnostic imaging; Peritoneal Neoplasms - diagnostic imaging; Peritoneal Neoplasms - therapy; Pseudomyxoma Peritonei - diagnostic imaging; Pseudomyxoma Peritonei - therapy
• ISSN: 0007-1285; 1748-880X; 1748-880X
• DOI: 10.1093/bjr/tqae102

Appendiceal mucinous neoplasms are rare and can be associated with the development of disseminated peritoneal disease known as pseudomyxoma peritonei (PMP). Mucinous tumours identified on appendicectomy are therefore followed up to assess for recurrence and the development of PMP. In addition, individuals who initially present with PMP and are treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) are followed up to assess for recurrence. However, despite the concerted efforts of multiple expert groups, the optimal imaging follow-up protocol is yet to be established. The purpose of this article is to review the available evidence for imaging surveillance in these populations to identify the optimum post-resection imaging follow-up protocol.