Overview of acute seizure management in US nursing homes

• Published in: Epilepsy & behavior 2024-09, Vol.158, p.109913, Article 109913
• Main Authors: O'Dwyer, Rebecca, Leppik, Ilo E., Eads, Pam, Long, Yuhan, Birnbaum, Angela K.
• Format: Article
• Language: English
• Subjects: Anticonvulsants - therapeutic use; Disease Management; Epilepsy; Female; Humans; Incidence; Male; Nursing homes; Nursing Homes - statistics & numerical data; Prevalence; Seizures - drug therapy; Treatment; United States - epidemiology
• ISSN: 1525-5050; 1525-5069; 1525-5069
• DOI: 10.1016/j.yebeh.2024.109913

•Only half of nursing homes had acute management and treatment seizure protocols.•Seizure protocols varied greatly across the surveyed medical directors.•Over three-quarters of patients received oral benzodiazepines as rescue therapy.•About one third of first-time seizures triggered a call for emergency services call. Residents in NH are more likely to be diagnosed with epilepsy or seizures, which are associated with higher mortality and complicate care. This setting provides unique challenges in the treatment of seizures however, little is known about current management practices in NH. Most studies in the literature concentrate on the use of antiseizure medications (ASMs) but little is known about the management of the acute seizure and clinical guidance is needed to ensure the safety of this vulnerable population. The objective of this study was to survey current practices, identifying knowledge deficits and inform future educational endeavors, including acute seizure action plans (ASAPs). A survey was developed pertaining to a broad spectrum of clinical aspects in the management of acute seizures in NH, distinguishing first time seizures from those in the setting of a known seizure disorder. It was sent to NH medical directors throughout the US and data was gathered from those who had at least one new case of new onset/epilepsy in the last 3 years. Ninety-one NH directors responded with 52 % having a seizure protocol. Nurses are responsible in the majority of cases for protocol activation. Regardless of the patient’s seizure history, rescue medications are given in the majority of cases, oral benzodiazepines, followed by intravenous and then rectal benzodiazepines. Newer intranasal and intramuscular formulations of benzodiazepines were less frequently prescribed. The most commonly prescribed ASM is levetiracetam, followed by lamotrigine, valproic acid and phenytoin. Staff training and in-service education occur infrequently. Respondents thought no-cost seizure education would be highly beneficial. Only approximately half of NH have protocols for the acute management of seizures. Rescue medications are given regardless of seizure history and often older ASMs are used for long-term management. Our study highlights areas of knowledge deficits and treatment areas for improvement, identifying the need and potential for ASAPs in NHs.