Fast, high-quality, and unshielded 0.2 T low-field mobile MRI using minimal hardware resources

• Published in: Magma (New York, N.Y.) N.Y.), 2024-12, Vol.37 (6), p.1091-1104
• Main Authors: Li, Lei, He, Qingyuan, Wei, Shufeng, Wang, Huixian, Wang, Zheng, Wei, Zhao, He, Hongyan, Xiang, Ce, Yang, Wenhui
• Format: Article
• Language: English
• Subjects: Adult; Algorithms; Basic Science - Engineering; Biomedical Engineering and Bioengineering; Brain - diagnostic imaging; Computer Appl. in Life Sciences; Deep Learning; Equipment Design; Female; Health Informatics; Healthy Volunteers; Humans; Image Processing, Computer-Assisted - methods; Imaging; Magnetic Resonance Imaging - instrumentation; Magnetic Resonance Imaging - methods; Male; Medicine; Medicine & Public Health; Phantoms, Imaging; Radiology; Research Article; Signal-To-Noise Ratio; Solid State Physics
• ISSN: 1352-8661; 1352-8661
• DOI: 10.1007/s10334-024-01184-5

Objective To propose a deep learning-based low-field mobile MRI strategy for fast, high-quality, unshielded imaging using minimal hardware resources. Methods Firstly, we analyze the correlation of EMI signals between the sensing coil and the MRI coil to preliminarily verify the feasibility of active EMI shielding using a single sensing coil. Then, a powerful deep learning EMI elimination model is proposed, which can accurately predict the EMI components in the MRI coil signals using EMI signals from at least one sensing coil. Further, deep learning models with different task objectives (super-resolution and denoising) are strategically stacked for multi-level post-processing to enable fast and high-quality low-field MRI. Finally, extensive phantom and brain experiments were conducted on a home-built 0.2 T mobile brain scanner for the evaluation of the proposed strategy. Results 20 healthy volunteers were recruited to participate in the experiment. The results show that the proposed strategy enables the 0.2 T scanner to generate images with sufficient anatomical information and diagnostic value under unshielded conditions using a single sensing coil. In particular, the EMI elimination outperforms the state-of-the-art deep learning methods and numerical computation methods. In addition, 2 × super-resolution (DDSRNet) and denoising (SwinIR) techniques enable further improvements in imaging speed and quality. Discussion The proposed strategy enables low-field mobile MRI scanners to achieve fast, high-quality imaging under unshielded conditions using minimal hardware resources, which has great significance for the widespread deployment of low-field mobile MRI scanners.