The effect of post-anesthetic administration of dexmedetomidine versus remifentanil on postoperative agitation of strabismus surgery in children: a randomized double-blind clinical trial

• Published in: Strabismus 2024-10, Vol.32 (4), p.1-251
• Main Authors: Sahmeddini, Mohammad Ali, Jamshidi, Mina, Panah, Ashkan, Salari, Mehrdad, Banifatemi, Mahsa, Kanaani Nejad, Fatemeh
• Format: Article
• Language: English
• ISSN: 0927-3972; 1744-5132; 1744-5132
• DOI: 10.1080/09273972.2024.2368703

: Postoperative agitation is a common complication of sevoflurane anesthesia in children and might lead to self-harm and recovery disruption. This study aimed to compare the prophylactic effect of dexmedetomidine and remifentanil on postoperative agitation after anesthesia with sevoflurane. : In this clinical trial, 60 children aged 2 to 7 years with ASA class І, II, candidates for elective strabismus surgery, were randomly assigned to three groups using block randomization. Patients in the first group D received 0.5 µgr/kg dexmedetomidine, the second group R received 0.1 µgr/kg remifentanil, and another group C received normal saline at the end of anesthesia. Children's agitation degree was measured by the Pediatric Anesthesia Emergence Delirium (PAED) scales and the 4-point agitation scale at the time of extubation, entering the recovery room, 10, 20, and 30 minutes after entrance. Data analysis was performed using descriptive and inferential statistical tests. : The postoperative agitation and pain were significantly lower among children who received dexmedetomidine compared with those in remifentanil and the control group (