Available evidence on fetal liver changes detected by ultrasound in pregnant women with gestational diabetes mellitus: Systematic review

The aim of this systematic review was to examine the available scientific literature on ultrasound‐detected fetal liver changes in pregnant women with gestational diabetes mellitus (GDM) and to explore the potential of these markers to inform clinical management and improve outcomes. A total of four...

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Bibliographic Details
Published in:Journal of clinical ultrasound 2024-10, Vol.52 (8), p.1121-1128
Main Authors: Da Correggio, Karine Souza, Galluzzo, Roberto Noya, Wangenheim, Aldo, Werner, Heron, Castro, Pedro Teixeira, Araujo Júnior, Edward, Onofre, Alexandre Sherlley Casimiro
Format: Article
Language:English
Subjects:
Diabetes mellitus
fetal liver
Fetuses
Gestational age
gestational diabetes mellitus
Liver
Predictive control
Pregnancy complications
systematic review
Ultrasound
ultrasound markers
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Summary:The aim of this systematic review was to examine the available scientific literature on ultrasound‐detected fetal liver changes in pregnant women with gestational diabetes mellitus (GDM) and to explore the potential of these markers to inform clinical management and improve outcomes. A total of four articles investigating fetal liver changes in GDM pregnancies were selected. The studies varied in methodology, gestational age studied, and diagnostic criteria for GDM. Fetal liver indices, such as fetal liver length and fetal liver volume, emerged as potential markers for identifying GDM and predicting adverse outcomes. Studies suggest an association between fetal liver changes and GDM, with implications for both maternal glycemic control and fetal metabolic adaptation. Variability in study methodology highlights the need for standardized approaches to assess fetal hepatic indices and their correlation with GDM outcomes. Assessment of fetal hepatic changes by ultrasound offers a promising way to evaluate gestational diabetes mellitus (GDM) pregnancies and predict outcomes. Standardized assessment methods, such as fetal liver length and fetal liver volume, may provide valuable insight into GDM progression and inform clinical decision‐making. Further research is warranted to validate these findings and explore additional markers to enhance prenatal care and improve outcomes.
ISSN:0091-2751
1097-0096
1097-0096
DOI:10.1002/jcu.23760