Safety of thyroidectomy in hospitalized patients: A descriptive analysis of the NSQIP thyroidectomy-targeted data

• Published in: The American journal of surgery 2024-07, p.115854, Article 115854
• Main Authors: Taylor, George A., Green, Rebecca L., Raman, Swathi, Kling, Sarah M., Fagenson, Alexander M., Zhao, Huaqing, Kuo, Lindsay E.
• Format: Article
• Language: English
• Subjects: Admitted thyroidectomy; Inpatient; Outpatient; Recurrent laryngeal
• ISSN: 0002-9610; 1879-1883; 1879-1883
• DOI: 10.1016/j.amjsurg.2024.115854

Some patients undergo thyroidectomy while hospitalized for a related or independent indication. Outcomes have not been described in this group. The 2016–2018 thyroidectomy-targeted NSQIP datasets were queried for patients admitted for ≥1 day preoperatively. 1:1 propensity score matching was employed to compare the outcomes of admitted patients to outpatients, including surgical and thyroidectomy-specific outcomes. Multivariable logistic regression determined factors associated with poor outcomes. Of 18,078 patients, 312 were admitted at least 1 day prior to surgery. Inpatients had higher ASA classifications and rates of several comorbidities compared to the general population. After propensity score matching, inpatients had higher rates of overall complications, unplanned reoperation, and bleeding. They also experienced higher rates of thyroidectomy-specific complications such as hypocalcemia and neck hematoma. By multivariable regression, admission prior to surgery was associated with development of any complications. Thyroidectomy in hospitalized patients carries an increased risk of complications. Patients requiring thyroidectomy while already hospitalized should be counseled accordingly. •Thyroidectomy on inpatients carries an increased risk of complications compared to outpatients.•Admission for any reason prior to thyroidectomy independently increases complication risk.•Postoperative resource utilization for already admitted thyroidectomy patients is high.•Patients requiring thyroidectomy while hospitalized should be counseled accordingly.