Ventricular Anatomical Differences—A Different Perspective on Endoscopic Treatment of Pediatric Hydrocephalus: Anomalies, Variations, and Deformations

• Published in: World neurosurgery 2024-11, Vol.191, p.e80-e91
• Main Authors: Evleksiz Karimzada, Demet, Can Ezgu, Mehmet, Karimzada, Gardashkhan, Izci, Yusuf
• Format: Article
• Language: English
• Subjects: Cerebral Ventricles - abnormalities; Cerebral Ventricles - diagnostic imaging; Cerebral Ventricles - surgery; Child; Child, Preschool; Children; Endoscope; Female; Humans; Hydrocephalus; Hydrocephalus - diagnostic imaging; Hydrocephalus - surgery; Infant; Lateral ventricle; Lateral Ventricles - abnormalities; Lateral Ventricles - diagnostic imaging; Lateral Ventricles - surgery; Male; Neuroendoscopy - methods; Retrospective Studies; Third ventricle; Third Ventricle - abnormalities; Third Ventricle - diagnostic imaging; Third Ventricle - surgery
• ISSN: 1878-8750; 1878-8769; 1878-8769
• DOI: 10.1016/j.wneu.2024.08.068

Endoscopic management of pediatric hydrocephalus is always challenging because of the different anatomical structure of the ventricles. The aim of this study is to document the endoscopic anatomy of the ventricular system and to show the variations and deformations. The study included 84 children who underwent endoscopic surgery for the treatment of hydrocephalus in the department of neurosurgery between 2017 and 2022. All preoperative and postoperative radiological images and intraoperative video recordings were retrospectively analyzed. Anatomy of the lateral ventricles and the third ventricle, variations, and deformations were detected and evaluated in detail. The mean age of the patients was 7.6 months. Myelomeningocele-encephalocele-associated hydrocephalus was the most common cause of hydrocephalus (38%), followed by postventriculitis in 21%, posthemorrhagic in 21%, and obstructive causes in 20% of cases, respectively. Endoscopic anomaly/variation or deformation was detected in 83% of all cases. Based on the preoperative radiological images, septum pellucidum anomaly/variation or deformation was the most common radiological finding in 64% of the cases. Lateral ventricle anomaly/variation or deformation was noted in 62% of the cases, and third ventricle anomaly/variation or deformation was observed as a radiological finding in 27% of the cases. The compliance of the brain deteriorates with increasing intracranial pressure in pediatric hydrocephalus and the intraventricular anatomical structures differ from the normal anatomy. Developmental anomalies of the ventricle are also significant and since all these variations are often unpredictable on preoperative imaging, awareness of endoscopic anatomy, variations, and deformations will improve operative safety in children.