Study on Intestinal Pressure after Implantation of Biaxial Actuated Artificial Anal Sphincter in Animal

Fecal incontinence (FI) referred to the inability to control the leakage of solid, liquid, or gaseous feces, the artificial anal sphincter (AAS) was the last resort for patients with FI except enterostomy. In order to the clinical application value of AAS was improved, the detection and analysis of...

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Bibliographic Details
Published in:Biomedical microdevices 2024-09, Vol.26 (3), p.38, Article 38
Main Authors: Hua, Fangfang, Yan, Guozheng, Wang, Lichao, Wu, Tong
Format: Article
Language:English
Subjects:
Actuators
Anal Canal - surgery
Animal research
Animals
Artificial Organs
Biological and Medical Physics
Biomedical Engineering and Bioengineering
Biophysics
Defecation
Depth perception
Engineering
Engineering Fluid Dynamics
Fecal incontinence
Fecal Incontinence - physiopathology
Feces
Intestine
Intestines - physiology
Nanotechnology
Pressure
Pressure effects
Real time
Sphincter
Swine
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Summary:Fecal incontinence (FI) referred to the inability to control the leakage of solid, liquid, or gaseous feces, the artificial anal sphincter (AAS) was the last resort for patients with FI except enterostomy. In order to the clinical application value of AAS was improved, the detection and analysis of intestinal pressure information was very necessary. Biaxial actuated artificial anal sphincter (BAAS) was a new type of AAS, which not only had a stable, long-term and safe energy supply, but also could provide real-time feedback of intestinal pressure information. In this paper, the BAAS was implanted into piglets for a long-term animal experiment. Piglets’ life habits, defecation habits and intestinal pressure were analyzed. The analysis results showed that the BAAS system had good feces control effect, when the actuator of the BAAS system was closed, there was basically no fecal leakage of piglets, and when the actuator of the BAAS system was opened, the piglets could defecate normally. Under the normal condition of the piglets’ health state and the BAAS’s operating state, the accuracy of the defecation perception reached to 65.79%. This study realized the in-depth study of the mechanism of piglets’ defecation, and provided guidance for the development of a new generation of AAS.
ISSN:1387-2176
1572-8781
1572-8781
DOI:10.1007/s10544-024-00722-1