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Effect of hiatal hernia and esophagogastric junction morphology on esophageal motility: Evidence from high‐resolution manometry studies

Background High‐resolution Manometry (HRM) is the most sensitive and specific test available for clinical assessment of hiatal hernia (HH), a common condition defined as the separation between the Lower Esophageal Sphincter (LES) and crural diaphragm (CD). While the link between HH and Gastroesophag...

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Published in:Neurogastroenterology and motility 2024-12, Vol.36 (12), p.e14929-n/a
Main Authors: Kayali, Stefano, Calabrese, Francesco, Pasta, Andrea, Marabotto, Elisa, Bodini, Giorgia, Furnari, Manuele, Savarino, Edoardo V., Savarino, Vincenzo, Giannini, Edoardo G., Zentilin, Patrizia
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Language:English
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Summary:Background High‐resolution Manometry (HRM) is the most sensitive and specific test available for clinical assessment of hiatal hernia (HH), a common condition defined as the separation between the Lower Esophageal Sphincter (LES) and crural diaphragm (CD). While the link between HH and Gastroesophageal Reflux Disease (GERD) is established, the potential association of HH with esophageal dysmotility, independently from GERD, is uncertain. This study aimed to analyze if HH, with or without GERD, can associate with esophageal motility disorders. Methods Consecutive patients without previous esophageal surgery who underwent HRM between 2018 and 2022 were enrolled. All patients with symptoms suggestive of GERD underwent impedance‐pH testing off‐therapy. HH was defined as a separation >1 cm between LES and CD, and esophagogastric junction (EGJ) morphology was classified as: Type I, when there was no separation between LES and CD; Type II, in case of minimal separation (>1 and 
ISSN:1350-1925
1365-2982
1365-2982
DOI:10.1111/nmo.14929