Specifically Decreased Thalamic Blood Flow Following COVID-19 Infection

Although long COVID refers to numerous COVID-19-related symptoms after infection, including depression, fatigue, anosmia, sleep disturbances, and brain fog, the etiology of long COVID remains largely unknown. A 41-year-old woman presented with a 3-week history of complete insomnia without drowsiness...

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Bibliographic Details
Published in:Clinical nuclear medicine 2024-11, Vol.49 (11), p.1041-1043
Main Authors: Matsubayashi, Taiki, Yokoyama, Kota, Tateishi, Ukihide, Yokota, Takanori, Sanjo, Nobuo
Format: Article
Language:English
Subjects:
Adult
Cerebrovascular Circulation
COVID-19 - complications
COVID-19 - diagnostic imaging
COVID-19 - physiopathology
Female
Humans
Thalamus - blood supply
Thalamus - diagnostic imaging
Thalamus - physiopathology
Tomography, Emission-Computed, Single-Photon
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Summary:Although long COVID refers to numerous COVID-19-related symptoms after infection, including depression, fatigue, anosmia, sleep disturbances, and brain fog, the etiology of long COVID remains largely unknown. A 41-year-old woman presented with a 3-week history of complete insomnia without drowsiness throughout the day after contracting COVID-19. SPECT using N -isopropyl-p-[ 123 I] iodoamphetamine showed a significant regional cerebral blood flow reduction in the bilateral thalamus. We diagnosed her as having insomnia accompanied by thalamic hypoperfusion related to COVID-19 infection. To our knowledge, this is the first case of reduced regional cerebral blood flow specifically confined to the thalamus.
ISSN:0363-9762
1536-0229
1536-0229
DOI:10.1097/RLU.0000000000005478