Neonatal outcomes after intervention for suspected renal colic in pregnancy

• Published in: European journal of obstetrics & gynecology and reproductive biology 2024-12, Vol.303, p.106-110
• Main Authors: Sun, Alec, Lyon, Madison, Bennett, Carrie, Sivalingam, Sri, Zampini, Anna, De, Smita
• Format: Article
• Language: English
• Subjects: Adult; Female; Humans; Infant, Newborn; Neonatal outcomes; Nephrolithiasis; Percutaneous nephrostomy; Pregnancy; Pregnancy Complications - diagnosis; Pregnancy Complications - therapy; Pregnancy Outcome; Renal Colic - diagnosis; Renal Colic - etiology; Renal Colic - therapy; Retrospective Studies; Stents; Ureteral stent; Ureteroscopy
• ISSN: 0301-2115; 1872-7654; 1872-7654
• DOI: 10.1016/j.ejogrb.2024.10.026

•Neonatal outcomes vary after ureteroscopy, stent, or nephrostomy tube placement in pregnant women with suspected renal colic.•NICU admission rates and gestational age at delivery were unfavorable in neonates of women managed with nephrostomy tubes.•No cases of respiratory distress syndrome or neonatal abstinence syndrome were seen in the ureteroscopy cohort. To compare neonatal outcomes following URS, stent, or PCN in pregnant women presenting with suspected renal colic. Women undergoing a procedure for suspected renal colic during pregnancy at a large multi-center institution between 2008 and 2022 were retrospectively reviewed and categorized by initial intervention. Neonatal outcomes were recorded and linked to maternal and obstetric data. Groups were compared by a Kruskal-Wallis, ANOVA, or Fisher’s Exact test, followed by pairwise post-hoc testing as appropriate (α = 0.05). Multivariate analyses were also conducted. 95 patients were analyzed, of whom 32 were managed with PCN, 47 with stent, and 16 with URS. Maternal baseline characteristics were similar between groups, except for lower gravidity and parity in the stent group. Rates of premature delivery did not differ, but gestational age at delivery was lower in the PCN group versus the stent and URS groups (p = 0.006 and p = 0.025, respectively). Neonatal Intensive Care Unit (NICU) admission rates were higher in the PCN group versus the stent and URS groups (p = 0.006 and 0.036, respectively). Respiratory distress syndrome significantly differed between groups (p = 0.041). Neonatal birth weight, Apgar scores, and other complications did not significantly differ. This study demonstrated higher rates of NICU admissions and lower gestational age at delivery for neonates born to mothers managed with PCN compared to stent and URS. Larger multi-institutional studies are warranted to further explore these associations.