Lipedematous scalp and lipedematous alopecia: a narrative review

Lipedematous scalp (LS) and lipedematous alopecia (LA) are uncommon conditions with an unclear cause. Over the past century, about 115 cases have been documented in the literature. It is unknown if these disorders are indeed so uncommon or if cases that accept the illness as a structural alteration...

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Bibliographic Details
Published in:Archives of dermatological research 2024-10, Vol.316 (10), p.723, Article 723
Main Author: Koç Yıldırım, Sema
Format: Article
Language:English
Subjects:
Alopecia
Alopecia - diagnosis
Alopecia - etiology
Alopecia - pathology
Baldness
Dermatology
Female
Humans
Lipedema - diagnosis
Lipedema - pathology
Lipedema - therapy
Male
Medicine
Medicine & Public Health
Review
Scalp
Scalp - pathology
Scalp Dermatoses - diagnosis
Scalp Dermatoses - pathology
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Summary:Lipedematous scalp (LS) and lipedematous alopecia (LA) are uncommon conditions with an unclear cause. Over the past century, about 115 cases have been documented in the literature. It is unknown if these disorders are indeed so uncommon or if cases that accept the illness as a structural alteration or are asymptomatic make the disease appear more uncommon than it is. Despite the fact that the majority of cases are seen in young and middle-aged people, the cases involving congenital, elderly, and children have also been reported. In the reported cases, female gender was observed to be dominant. The most significant clinical characteristics include felty swelling of the scalp in both disorders, diffusely or locally enlarged subcutaneous tissue with a swampy, spongy feel, and varied degrees of alopecia in LA. There is still much to learn about the pathogenetic mechanisms and therapeutic approaches for LA and LS. In this article, I review the general clinical characteristics, supposed pathogenetic mechanisms, histopathologic characteristics, diagnostic procedures, and management strategies for LS and LA.
ISSN:1432-069X
0340-3696
1432-069X
DOI:10.1007/s00403-024-03478-z