Comparison of site-specific tensile, compressive, and friction properties of human tibiofemoral joint cartilage and their relationship to degeneration

Site-specific differences in the compressive properties of tibiofemoral joint articular cartilage are well-documented, while exploration of tensile and frictional properties in humans remains limited. Thus, this study aimed to characterize and compare the tensile, compressive and frictional properti...

Full description

Saved in:
Bibliographic Details
Published in:Journal of biomechanics 2024-12, Vol.177, p.112386, Article 112386
Main Authors: Ristaniemi, Aapo, Tuppurainen, Juuso, Jäntti, Jiri, Nippolainen, Ervin, Afara, Isaac O., Mononen, Mika E., Korhonen, Rami K., Mäkelä, Janne T.A.
Format: Article
Language:English
Subjects:
Adult
Aged
Biomechanical Phenomena
Cartilage
Cartilage (articular)
Cartilage, Articular - physiology
Coefficient of friction
Compression
Compressive properties
Compressive Strength - physiology
Data analysis
Degeneration
Equilibrium
Female
Femur
Femur - physiology
Friction
Friction - physiology
Humans
Joints (anatomy)
Knee Joint - physiology
Male
Middle Aged
Prostheses
Stress, Mechanical
Surgical implants
Tensile properties
Tensile strength
Tensile Strength - physiology
Tensile tests
Tibia
Tibia - physiology
Tibiofemoral Joint
Tissue engineering
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Site-specific differences in the compressive properties of tibiofemoral joint articular cartilage are well-documented, while exploration of tensile and frictional properties in humans remains limited. Thus, this study aimed to characterize and compare the tensile, compressive and frictional properties of articular cartilage across different sites of the tibiofemoral joint, and to establish relationships between these properties and cartilage degeneration. We cut human tibiofemoral joint (N = 5) cartilage surfaces into tensile testing samples (n = 155) and osteochondral plugs (n = 40) to determine the tensile, friction and compressive properties, as well as OARSI grades. We performed comparisons between sites using a linear mixed model and analyzed relationships with OARSI grade using Spearman’s rank correlation. Cartilage samples were mostly healthy: 56 % were grade 0 or 1, 26 % grade 2, and 18 % grade 3 or higher. In tension, the medial femur was more compliant and viscous compared to the lateral femur (p 
ISSN:0021-9290
1873-2380
1873-2380
DOI:10.1016/j.jbiomech.2024.112386