Clinical Frailty Scale Predicts Outcomes After Elective Thoracic Endovascular Aortic Repair: A Single-Center Retrospective Cohort Study

• Published in: Journal of endovascular therapy 2024-12, p.15266028241302658
• Main Authors: Tsushima, Shingo, Shibata, Tsuyoshi, Iba, Yutaka, Nakajima, Tomohiro, Nakazawa, Junji, Miura, Shuhei, Arihara, Ayaka, Nakanishi, Keitaro, Mizuno, Takakimi, Mukawa, Kei, Kawaharada, Nobuyoshi
• Format: Article
• Language: English
• ISSN: 1526-6028; 1545-1550; 1545-1550
• DOI: 10.1177/15266028241302658

The Clinical Frailty Scale (CFS), used to define frail patients, is significantly associated with clinical outcomes. The CFS can predict postoperative prognosis after cardiovascular procedures. However, no reports exist on the relationship between frailty defined by the CFS and thoracic endovascular aortic repair (TEVAR) outcomes. We analyzed data obtained from patients who underwent TEVAR between January 2011 and December 2021. Frailty was assessed using the 9-point CFS and was defined as a score of ≥5 points. The primary outcome was the 5-year overall survival rate. The secondary outcomes included the rate of freedom from aneurysm-related death at 5 years, postoperative complications, length of stay, rate of nonhome discharge, need for mobility assistance, 30-day mortality rate, and re-intervention rate. Of 331 patients who underwent TEVAR, 186 were included. The mean age of frail (n=36) and nonfrail (n=150) patients was 73.2 ± 7.3 years and 70.9 ± 9.0 years, respectively (p=0.15). The length of stay (17 [9-39] vs 11 [10-16] days; p=0.09) and re-intervention rate (8.3% vs 13.3%; p=0.58) were not significantly different, although frail patients had a higher rate of nonhome discharge (33.3% vs 4.7%; p