The dysregulation of PARP9 expression is linked to apoptosis and DNA damage in gastric cancer cells

Gastric cancer (GC) is a highly malignant gastrointestinal tumor characterized by difficult early diagnosis and poor prognosis. Therefore, it is imperative to explore potential therapeutic targets for gastric cancer. PARP9 is abnormally expressed in a variety of tumors and is associated with tumor c...

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Bibliographic Details
Published in:PloS one 2024-12, Vol.19 (12), p.e0316476
Main Authors: Li, Yating, Wang, Xing, Liu, Xiaolong, Li, Xiangjie, Zhang, Jianling, Li, Yulan
Format: Article
Language:English
Subjects:
Analysis
Apoptosis
Apoptosis - genetics
Assaying
Bioinformatics
Biology and Life Sciences
Cancer
Cell Line, Tumor
Cell migration
Cell Movement - genetics
Cell proliferation
Cell Proliferation - genetics
Cholecystokinin
Damage
Data analysis
Deoxyribonucleic acid
Development and progression
DNA
DNA Damage
DNA repair
Enzymes
Female
Flow cytometry
Gastric cancer
Gene expression
Gene Expression Regulation, Neoplastic
Gene sequencing
Genetic aspects
Health aspects
Humans
Identification and classification
Male
MAP kinase
Medical prognosis
Medicine and Health Sciences
Mortality
Neoplasm Proteins
Phenotypes
Physiological aspects
Plasmids
Poly(ADP-ribose) Polymerases - genetics
Poly(ADP-ribose) Polymerases - metabolism
Prognosis
Proteins
Reagents
Research and Analysis Methods
Risk factors
RNA
RNA sequencing
Signal transduction
Stomach cancer
Stomach Neoplasms - genetics
Stomach Neoplasms - metabolism
Stomach Neoplasms - pathology
Therapeutic targets
Tumor cell lines
Tumors
Wound healing
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