Engineering a solar formic acid/pentose (SFAP) pathway in Escherichia coli for lactic acid production

Microbial CO2 fixation into lactic acid (LA) is an important approach for low-carbon biomanufacturing. Engineering microbes to utilize CO2 and sugar as co-substrates can create efficient pathways through input of moderate reducing power to drive CO2 fixation into product. However, to achieve complet...

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Bibliographic Details
Published in:Metabolic engineering 2024-05, Vol.83, p.150-159
Main Authors: Zhang, Yajing, Sun, Tao, Liu, Linqi, Cao, Xupeng, Zhang, Weiwen, Wang, Wangyin, Li, Can
Format: Article
Language:English
Subjects:
biobased products
carbon dioxide
catabolism
CO2 fixation
Escherichia coli
feedstocks
formates
formic acid
glucose
glycolysis
Lactic acid
organic carbon
oxidation
pentose phosphate cycle
pentoses
photovoltaic cells
Solar formate
value added
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