A sex-specific switch in a single glial cell patterns the apical extracellular matrix

Apical extracellular matrix (aECM) constitutes the interface between every tissue and the outside world. It is patterned into diverse tissue-specific structures through unknown mechanisms. Here, we show that a male-specific genetic switch in a single C. elegans glial cell patterns the overlying aECM...

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Bibliographic Details
Published in:Current biology 2023-10, Vol.33 (19), p.4174-4186.e7
Main Authors: Fung, Wendy, Tan, Taralyn M., Kolotuev, Irina, Heiman, Maxwell G.
Format: Article
Language:English
Subjects:
aECM
Animals
C. elegans
Caenorhabditis elegans - genetics
cuticle
electron microscopy
extracellular matrix
Extracellular Matrix - metabolism
Female
gene expression
glia
Hedgehog Proteins - metabolism
Male
males
Neuroglia
Neurons
sensory neurons
sex differences
sex reversal
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