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Comment on the mechanical properties of the amyloid fibre, poly(ValGlyGlyLeuGly), obtained by a novel AFM methodology
Poly(ValGlyGlyLeuGly) is an elastin-like polypeptide belonging to the glycine-rich sequences of elastin [1]. When suspended in water and deposited on silicon wafers, it self-assembles in amyloid-like fibres. These fibres, and those from similar sequences show a remarkable resistance to bending, tend...
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Published in: | Journal of materials science 2008, Vol.43 (1), p.395-397 |
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creator | Flamia, R. Zhdan, P. A. Castle, J. E. Tamburro, A. M. |
description | Poly(ValGlyGlyLeuGly) is an elastin-like polypeptide belonging to the glycine-rich sequences of elastin [1]. When suspended in water and deposited on silicon wafers, it self-assembles in amyloid-like fibres. These fibres, and those from similar sequences show a remarkable resistance to bending, tending to remain straight across large fields of view, even at bridging points between fibres [2, 3]. We have now confirmed this apparent axial stiffness by measurement of mechanical properties using atomic force microscopy (AFM). |
doi_str_mv | 10.1007/s10853-007-2289-z |
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subjects | Aminoacid polymers Applied sciences Characterization and Evaluation of Materials Chemistry and Materials Science Classical Mechanics Crystallography and Scattering Methods Exact sciences and technology Letter Materials Science Mechanical properties Physicochemistry of polymers Polymer Sciences Solid Mechanics Synthetic biopolymers |
title | Comment on the mechanical properties of the amyloid fibre, poly(ValGlyGlyLeuGly), obtained by a novel AFM methodology |
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