Detection of the unique sugars virenose and dihydrohydroxystreptose from Coxiella burnetii using alditol acetylation and liquid chromatography mass spectroscopy

The bacterium Coxiella burnetii causes Q-Fever in humans and coxiellosis in animals. This work presents a robust, sensitive and selective method for the identification of two unique sugars found in the lipopolysaccharide of C. burnetii. The sugars were derivatised using alditol acetylation and ident...

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Bibliographic Details
Published in:Carbohydrate research 2025-07, Vol.553, p.109524, Article 109524
Main Authors: Webb, Lawrence, Graves, Stephen R., Stenos, John, Plain, Karren M., Conlan, Xavier A.
Format: Article
Language:English
Subjects:
Acetylation
Chromatography, High Pressure Liquid
Coxiella burnetii
Coxiella burnetii - chemistry
Dihydrohydroxystreptose
Lipopolysaccharide
Lipopolysaccharides - chemistry
Mass Spectrometry
Q-fever
Virenose
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