Oxidative Stress, Inflammation, and Pulmonary Function Assessment in Rats Exposed to Laboratory-Generated Pollutant Mixtures

Oxidative stress may mediate adverse health effects of many inhaled pollutants. Cardiopulmonary responses of Sprague-Dawley rats to inhalation of whole or filtered gasoline engine exhaust (GEE, FGEE); simulated downwind coal emission atmospheres (SDCAs) from two types of coal, each tested at two con...

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Bibliographic Details
Published in:Journal of Toxicology and Environmental Health, Part A Part A, 2008-01, Vol.71 (20), p.1352-1362
Main Authors: Seagrave, JeanClare, Campen, Matthew J., McDonald, Jacob D., Mauderly, Joe L., Rohr, Annette C.
Format: Article
Language:English
Subjects:
Air Pollutants - analysis
Air Pollutants - toxicity
Animals
Atmosphere Exposure Chambers
Bronchoalveolar Lavage Fluid
Heart - drug effects
Inflammation - etiology
Inflammation - metabolism
Liver - drug effects
Luminescence
Lung - drug effects
Male
Oxidative Stress - drug effects
Rats
Rats, Sprague-Dawley
Respiratory Function Tests
Thiobarbituric Acid Reactive Substances - metabolism
Vehicle Emissions - toxicity
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