The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering

In the literature there are conflicting reports on the optimal scaffold mean pore size required for successful bone tissue engineering. This study set out to investigate the effect of mean pore size, in a series of collagen–glycosaminoglycan (CG) scaffolds with mean pore sizes ranging from 85 μm to...

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Bibliographic Details
Published in:Biomaterials 2010-01, Vol.31 (3), p.461-466
Main Authors: Murphy, Ciara M., Haugh, Matthew G., O'Brien, Fergal J.
Format: Article
Language:English
Subjects:
3T3 Cells
Advanced Basic Science
Animals
Biocompatible Materials - chemistry
Biocompatible Materials - metabolism
Bone and Bones - cytology
Bone and Bones - physiology
Bone tissue engineering
Cell Adhesion
Cell Movement
Cell Proliferation
Cells, Cultured
Collagen
Collagen - chemistry
Collagen - metabolism
Dentistry
Glycosaminoglycans - chemistry
Glycosaminoglycans - metabolism
Materials Testing
Mice
Microstructure
Osteoblasts - cytology
Osteoblasts - physiology
Porosity
Scaffold
Tissue Engineering - instrumentation
Tissue Engineering - methods
Tissue Scaffolds - chemistry
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