Organization of the autoantibody repertoire in healthy newborns and adults revealed by system level informatics of antigen microarray data

The immune system is essential to body defense and maintenance. Specific antibodies to foreign invaders function in body defense, and it has been suggested that autoantibodies binding to self molecules are important in body maintenance. Recently, the autoantibody repertoires in the bloods of healthy...

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Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS 2009-08, Vol.106 (34), p.14484-14489
Main Authors:	Madi, Asaf, Hecht, Inbal, Bransburg-Zabary, Sharron, Merbl, Yifat, Pick, Adi, Zucker-Toledano, Merav, Quintana, Francisco J, Tauber, Alfred I, Cohen, Irun R, Ben-Jacob, Eshel
Format:	Article
Language:	English
Subjects:	Adult Algorithms Antibodies Antigens Autoantibodies Autoantibodies - analysis Autoantigens - classification Autoantigens - immunology Autoimmune diseases Autoimmune Diseases - immunology Autoimmunity - immunology Biological Sciences Blood Cluster Analysis Correlations Female Humans Immune system immunoglobulin G Immunoglobulin G - analysis immunoglobulin M Immunoglobulin M - analysis Immunoglobulins - analysis Infant, Newborn Informatics - methods Isotypes Maternal & child health Maternal-Fetal Exchange - immunology Microarray Analysis - methods microarray technology Molecules mothers neonates Newborns Placenta - immunology Pregnancy Principal components analysis Reactivity Studies Women young adults
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