The effect of total and anterior partial fundoplication on antireflux mechanisms of the gastroesophageal junction

The effect of total (Nissen) and anterior partial fundoplication (APF) for the surgical treatment of gastroesophageal reflux disease (GERD) on the motor behavior of the esophagogastric axis has not been fully assessed. The purpose of this study was to assess any alterations in lower esophageal sphin...

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Bibliographic Details
Published in:The American journal of surgery 2004-07, Vol.188 (1), p.39-44
Main Authors: Chrysos, Emmanuel, Athanasakis, Elias, Pechlivanides, George, Tzortzinis, Anastasios, Mantides, Apostolos, Xynos, Evaghelos
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Digestive system
Esophagogastric Junction - physiopathology
Female
Fundoplication - adverse effects
Fundoplication - methods
Gastroesophageal Reflux - physiopathology
Gastroesophageal Reflux - surgery
Gastroesophageal reflux disease
Gastrointestinal diseases
General aspects
Health care
Hernias
Humans
Lower esophageal sphincter pressure
Male
Manometry
Medical sciences
Middle Aged
Nissen fundoplication
Pressure
Statistics, Nonparametric
Surgery
Throat
Transient relaxations of lower esophageal pressure
Watson anterior hemifundoplication
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Summary:The effect of total (Nissen) and anterior partial fundoplication (APF) for the surgical treatment of gastroesophageal reflux disease (GERD) on the motor behavior of the esophagogastric axis has not been fully assessed. The purpose of this study was to assess any alterations in lower esophageal sphincter (LES) and gastric fundus motor parameters in GERD patients after Nissen or APF fundoplication. Twenty four patients with documented GERD underwent either laparoscopic Nissen fundoplication (n = 12) or laparoscopic APF (n = 12). Preoperative and postoperative stationary esophageal manometry included assessment of LES resting and postdeglutition relaxation pressures, intragastric pressure, and LES transient relaxations in the left lateral and upright positions and after gastric distension. Both types of fundoplication resulted in significant increases in LES resting ( P
ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2003.10.023