Pleomorphic adenoma with predominant plasmocytoid myoepithelial cells: A diagnostic pitfall in aspiration cytology. Case report and review of the literature

Fine‐needle aspiration (FNA) biopsy of the salivary gland is a sensitive and specific diagnostic tool. However, diagnostic problems are sometimes encountered in interpreting some cases, not only in differentiating benign from malignant cases but also in the specific classification of these neoplasms...

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Bibliographic Details
Published in:Diagnostic cytopathology 2009-01, Vol.37 (1), p.56-60
Main Authors: Pusztaszeri, Marc, Braunschweig, Richard, Mihaescu, Anca
Format: Article
Language:English
Subjects:
Adenoma, Pleomorphic - diagnosis
Adenoma, Pleomorphic - pathology
Aged
aspiration biopsy
Biopsy, Fine-Needle
cytology
Diagnosis, Differential
Female
Humans
myoepithelioma
Myoepithelioma - diagnosis
Myoepithelioma - pathology
pleomorphic adenoma
salivary gland neoplasm
Salivary Gland Neoplasms - diagnosis
Salivary Gland Neoplasms - pathology
Salivary Glands - pathology
ThinPrep
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Summary:Fine‐needle aspiration (FNA) biopsy of the salivary gland is a sensitive and specific diagnostic tool. However, diagnostic problems are sometimes encountered in interpreting some cases, not only in differentiating benign from malignant cases but also in the specific classification of these neoplasms. We report a case of a pleomorphic adenoma with predominant plasmocytoid myoepithelial cells arising in minor salivary glands from the hard palate in a 78‐year‐old patient, which was falsely diagnosed as a carcinoma on liquid‐based cytology (ThinPrep (TP)). The differential diagnosis of salivary gland tumors with predominant myoepithelial cells on FNA biopsy is discussed. Diagn. Cytopathol. 2009. © 2008 Wiley‐Liss, Inc.
ISSN:8755-1039
1097-0339
DOI:10.1002/dc.20954