Comparison of mortality rates after acute myocardial infarction in smokers versus nonsmokers

According to several reports, patients who smoke paradoxically have favorable outcomes after acute myocardial infarctions (AMIs) compared with nonsmokers. The Optimal Trial in Myocardial Infarction With the Angiotensin II Antagonist Losartan evaluated 5,477 high-risk patients after AMIs. Patients wi...

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Bibliographic Details
Published in:The American journal of cardiology 2004-09, Vol.94 (5), p.632-636
Main Authors: Jaatun, Hans Jakob, Sutradhar, Santosh C., Dickstein, Kenneth
Format: Article
Language:English
Subjects:
Age Factors
Aged
Biological and medical sciences
Cardiology
Cardiology. Vascular system
Comorbidity
Comparative analysis
Coronary heart disease
Female
Heart
Heart attacks
Humans
Male
Medical sciences
Middle Aged
Mortality
Myocardial Infarction - epidemiology
Myocardial Infarction - mortality
Myocarditis. Cardiomyopathies
Outcome Assessment (Health Care)
Prospective Studies
Smoking
Smoking - epidemiology
Smoking - mortality
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Summary:According to several reports, patients who smoke paradoxically have favorable outcomes after acute myocardial infarctions (AMIs) compared with nonsmokers. The Optimal Trial in Myocardial Infarction With the Angiotensin II Antagonist Losartan evaluated 5,477 high-risk patients after AMIs. Patients with a history of smoking had a 17% smaller risk for death (hazard ratio 0.83, p = 0.005) compared with nonsmokers. After adjustment for age only, without correction for other co-morbidities or risk factors, the lower all-cause mortality in smoker population was explained by the smokers' generally younger age, with better prognoses due to their age.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2004.05.029