Respiratory changes in inferior vena cava diameter are helpful in predicting fluid responsiveness in ventilated septic patients

To evaluate the extent to which respiratory changes in inferior vena cava (IVC) diameter can be used to predict fluid responsiveness. Prospective clinical study. Hospital intensive care unit. Twenty-three patients with acute circulatory failure related to sepsis and mechanically ventilated because o...

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Bibliographic Details
Published in:Intensive care medicine 2004-09, Vol.30 (9), p.1740-1746
Main Authors: BARBIER, Christophe, LOUBIERES, Yann, SCHMIT, Christophe, HAYON, Jan, RICOME, Jean-Louis, JARDIN, Francois, VIEILLARD-BARON, Antoine
Format: Article
Language:English
Subjects:
Adult
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood Pressure
Central Venous Pressure
Echocardiography, Doppler
Heart Function Tests
Heart Rate
Humans
Intensive care medicine
Intensive Care Units
Medical sciences
Middle Aged
Prognosis
Prospective Studies
Respiration, Artificial
Respiratory Insufficiency - etiology
Respiratory Insufficiency - physiopathology
Respiratory Insufficiency - therapy
Sepsis - complications
Sepsis - physiopathology
Sepsis - therapy
Vena Cava, Inferior - pathology
Vena Cava, Inferior - physiopathology
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Summary:To evaluate the extent to which respiratory changes in inferior vena cava (IVC) diameter can be used to predict fluid responsiveness. Prospective clinical study. Hospital intensive care unit. Twenty-three patients with acute circulatory failure related to sepsis and mechanically ventilated because of an acute lung injury. Inferior vena cava diameter (D) at end-expiration (Dmin) and at end-inspiration (Dmax) was measured by echocardiography using a subcostal approach. The distensibility index of the IVC (dIVC) was calculated as the ratio of Dmax - Dmin / Dmin, and expressed as a percentage. The Doppler technique was applied in the pulmonary artery trunk to determine cardiac index (CI). Measurements were performed at baseline and after a 7 ml/kg volume expansion using a plasma expander. Patients were separated into responders (increase in CI > or =15%) and non-responders (increase in CI
ISSN:0342-4642
1432-1238
DOI:10.1007/s00134-004-2259-8