Could cells from menstrual blood be a new source for cell-based therapies?

Summary Human endometrium is a highly regenerative tissue and contains a low number of cells which have high replicative ability and differentiation efficiency. This has been identified by many scientists. When the fresh growth of tissue and blood vessels is shed during each menstrual cycle, some ce...

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Bibliographic Details
Published in:Medical hypotheses 2009-03, Vol.72 (3), p.252-254
Main Authors: Zhang, Man-Jing, Liu, Bin, Xia, Wei, Sun, Zhi-Yong, Lu, Kai-Hua
Format: Article
Language:English
Subjects:
Blood Cells - transplantation
Blood Component Transfusion - methods
Blood Component Transfusion - trends
Cell Transplantation - methods
Endometrium - cytology
Female
Humans
Internal Medicine
Menstruation - blood
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Summary:Summary Human endometrium is a highly regenerative tissue and contains a low number of cells which have high replicative ability and differentiation efficiency. This has been identified by many scientists. When the fresh growth of tissue and blood vessels is shed during each menstrual cycle, some cells with regenerative capabilities are present. Reports have also indicated that these cells possess the capacity to trans-differentiate into mesodermal, ectodermal and endodermal lineages by using standard commercially available culture reagents and methodologies. Given the ease of extraction and pluripotency of this cell population, we propose it as a novel alternative to current cells sources for cell-based therapies.
ISSN:0306-9877
1532-2777
DOI:10.1016/j.mehy.2008.10.021