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Reproducibility of fMRI at 1.5 T in a strictly controlled motor task
Reproducibility of functional MRI (fMRI) data has been controversial. This issue was examined in this study by evaluating a strictly controlled voluntary force‐matching handgrip task. Handgrip force, electromyogram (EMG), and fMRI data of brain activity were simultaneously recorded during the task p...
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Published in: | Magnetic resonance in medicine 2004-10, Vol.52 (4), p.751-760 |
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Main Authors: | , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Reproducibility of functional MRI (fMRI) data has been controversial. This issue was examined in this study by evaluating a strictly controlled voluntary force‐matching handgrip task. Handgrip force, electromyogram (EMG), and fMRI data of brain activity were simultaneously recorded during the task performance. The task was repeated three times in each of the two experimental sessions. While force remained unchanged and EMG showed little variation across trials and sessions, the results revealed that fMRI‐measured brain signals varied significantly among individual trials. However, the averaged fMRI signals over the three trials did not show significant difference between the two sessions. Our data suggest that fMRI is better at defining brain activation qualitatively than quantitatively, i.e., the locations of the activation areas could be reproduced quite reliably while their sizes fluctuated substantially. Magn Reson Med 52:751–760, 2004. © 2004 Wiley‐Liss, Inc. |
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ISSN: | 0740-3194 1522-2594 |
DOI: | 10.1002/mrm.20211 |