Effect of detraining on bone and muscle tissue in subjects with chronic spinal cord injury after a period of electrically-stimulated cycling: a small cohort study

• Published in: Journal of rehabilitation medicine 2009-03, Vol.41 (4), p.282-285
• Main Authors: Frotzler, Angela, Coupaud, Sylvie, Perret, Claudio, Kakebeeke, Tanja H, Hunt, Kenneth J, Eser, Prisca
• Format: Article
• Language: English
• Subjects: Adult; Bicycling; Bone Density - physiology; Bone mineral density; Bones; Chronic Disease; Cohort Studies; Electric Stimulation Therapy - methods; Female; Follow-Up Studies; Humans; Induced; Male; Middle Aged; Muscle Strength - physiology; Muscle, Skeletal - pathology; Muscle, Skeletal - physiopathology; Muscles; Osteoporosis - etiology; Parameters; Spinal cord injuries; Spinal Cord Injuries - complications; Spinal Cord Injuries - physiopathology; Spinal Cord Injuries - rehabilitation
• ISSN: 1650-1977; 1651-2081
• DOI: 10.2340/16501977-0321

To investigate adaptive changes in bone and muscle parameters in the paralysed limbs after detraining or reduced functional electrical stimulation (FES) induced cycling following high-volume FES-cycling in chronic spinal cord injury. Five subjects with motor-sensory complete spinal cord injury (age 38.6 years, lesion duration 11.4 years) were included. Four subjects stopped FES-cycling completely after the training phase whereas one continued reduced FES-cycling (2-3 times/week, for 30 min). Bone and muscle parameters were assessed in the legs using peripheral quantitative computed tomography at 6 and 12 months after cessation of high-volume FES-cycling. Gains achieved in the distal femur by high-volume FES-cycling were partly maintained at one year of detraining: 73.0% in trabecular bone mineral density, 63.8% in total bone mineral density, 59.4% in bone mineral content and 22.1% in muscle cross-sectional area in the thigh. The subject who continued reduced FES-cycling maintained 96.2% and 95.0% of the previous gain in total and trabecular bone mineral density, and 98.5% in muscle cross-sectional area. Bone and muscle benefits achieved by one year of high-volume FES-cycling are partly preserved after 12 months of detraining, whereas reduced cycling maintains bone and muscle mass gained. This suggests that high-volume FES-cycling has clinical relevance for at least one year after detraining.