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Association between Cigarette Consumption and Proteinuria in Healthy Japanese Men and Women from an Occupational Population

Association between Cigarette Consumption and Proteinuria in Healthy Japanese Men and Women from an Occupational Population:Vuichi YAMADA, et al. Department of Social and Environmental Medicine (Hygiene), Kanazawa Medical University - The association between cigarette consumption and prevalence of m...

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Published in:Journal of Occupational Health 2004-09, Vol.46 (5), p.365-373
Main Authors: Yamada, Yuichi, Noborisaka, Yuka, Ishizaki, Masao, Honda, Ryumon, Tsuritani, Ikiko, Yamada, Seiji
Format: Article
Language:English
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Summary:Association between Cigarette Consumption and Proteinuria in Healthy Japanese Men and Women from an Occupational Population:Vuichi YAMADA, et al. Department of Social and Environmental Medicine (Hygiene), Kanazawa Medical University - The association between cigarette consumption and prevalence of mild proteinuria (30-99 mg/dl of albumin) was analyzed in 11,569 male and 4,715 female workers aged 18-67 yr recruited from an occupational population. Proteinuria was found in 274 (2.4%) of the total male workers and in 50 (1.1%) of the total females. Stepwise logistic regression analyses showed that sex, suspected diabetes mellitus, blood pressure (BP) and Brinkman Index (BI) levels (0,1-199, 200-499, 500-799, 800-) were significantly related to proteinuria, and that the odds ratio of each BI level for proteinuria was 1.11(C.I.:1.01-1.67). In the subjects aged 50 yr or older, after excluding those suspected of having hypertension and! or diabetes mellitus, the odds ratio reached 1.37 (C.I.:1.15-1.63), with the gender difference then no longer significant. The odds ratio for proteinuria was calculated as 5.44(C.I.:2.27-13.0) in male and female smokers having a BI of 500 or above and normal-high BP (130-139/85-89 mmHg) in comparison with nonsmokers having normal BP (
ISSN:1341-9145
1348-9585
1348-9585
DOI:10.1539/joh.46.365