Virtual optimization of self-expandable braided wire stents

Abstract At present, the deployment of self-expandable braided stents has become a common and widely used minimally invasive treatment for stenotic lesions in the cardiovascular, gastrointestinal and respiratory system. To improve these revascularization procedures (e.g. increase the positioning acc...

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Bibliographic Details
Published in:Medical engineering & physics 2009-05, Vol.31 (4), p.448-453
Main Authors: De Beule, Matthieu, Van Cauter, Sofie, Mortier, Peter, Van Loo, Denis, Van Impe, Rudy, Verdonck, Pascal, Verhegghe, Benedict
Format: Article
Language:English
Subjects:
Blood Vessel Prosthesis
Braided wire stent
Computer Simulation
Computer-Aided Design
Elastic Modulus
Equipment Design
Equipment Failure Analysis
Finite element
Humans
Models, Biological
Optimization
PyFormex
Radiology
Reproducibility of Results
Sensitivity and Specificity
Stents
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Summary:Abstract At present, the deployment of self-expandable braided stents has become a common and widely used minimally invasive treatment for stenotic lesions in the cardiovascular, gastrointestinal and respiratory system. To improve these revascularization procedures (e.g. increase the positioning accuracy) the optimal strategy lies in the further development of the stent design. In the context of optimizing braided stent designs, computational models can provide an excellent research tool complementary to analytical models. In this study, a finite element based modelling strategy is proposed to investigate and optimize the mechanics of braided stents. First a geometrical and finite element model of a braided Urolume endoprosthesis was built with the open source pyFormex design tool. The results of the reference simulation of the Urolume stent are in close agreement with both analytical and experimental data. Subsequently, a simplex-based design optimization algorithm automatically adjusts the reference Urolume geometry to facilitate precise positioning by reducing the foreshortening with 20% while maintaining the radial stiffness. Therefore, the proposed modelling strategy appears to be a promising optimization methodology in braided stent design.
ISSN:1350-4533
1873-4030
DOI:10.1016/j.medengphy.2008.11.008