Obesity and weight gain as risk factors for erosive oesophagitis in men

Summary Background  Although obesity and weight gain increase the risk for symptoms of gastro‐oesophageal reflux disease, their association with erosive oesophagitis is still unclear in the male population. Aim  To evaluate, in men, the association of body mass index (BMI) and weight gain with endos...

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Bibliographic Details
Published in:Alimentary pharmacology & therapeutics 2009-05, Vol.29 (9), p.1042-1052
Main Authors: NAM, S. Y., CHOI, I. J., NAM, B. H., PARK, K. W., KIM, C. G.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Body Mass Index
Digestive system
Esophagitis - diagnosis
Esophagitis - epidemiology
Esophagitis - etiology
Esophagoscopy
Esophagus
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Korea - epidemiology
Male
Medical sciences
Metabolic diseases
Middle Aged
Obesity
Obesity - complications
Other diseases. Semiology
Pharmacology. Drug treatments
Weight Gain
Young Adult
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Summary:Summary Background  Although obesity and weight gain increase the risk for symptoms of gastro‐oesophageal reflux disease, their association with erosive oesophagitis is still unclear in the male population. Aim  To evaluate, in men, the association of body mass index (BMI) and weight gain with endoscopically proven erosive oesophagitis. Methods  A total of 8571 Korean men in a comprehensive screening cohort were enrolled. Effects of BMI and abdominal obesity on erosive oesophagitis were estimated with odds ratios (ORs) and 95% confidence intervals (CIs) using logistic regression analysis. We also evaluated the association between erosive oesophagitis and BMI change after 1–3 years. Results  The prevalence of erosive oesophagitis was 6.4% (552/8571). In univariate analysis, the ORs for erosive oesophagitis increased as BMI or waist circumference increased (P for trend
ISSN:0269-2813
1365-2036
DOI:10.1111/j.1365-2036.2009.03965.x