Relationships between age, drugs, oral sensorial complaints and salivary profile

The aim of this study was to investigate the relationships between oral sensorial complaints (OSCs) and salivary flow rate, composition and drug consumption of subjects aged 18–90 years. The results were correlated with both drug consumption and OSCs. Only individuals who were free of conditions tha...

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Bibliographic Details
Published in:Archives of oral biology 2005, Vol.50 (1), p.7-16
Main Authors: Nagler, Rafael M., Hershkovich, Oded
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age
Age Factors
Aged
Aged, 80 and over
Burning mouth syndrome
Burning Mouth Syndrome - metabolism
Burning Mouth Syndrome - physiopathology
Composition
Dentistry
Drug Prescriptions
Female
Flow rate
Humans
Longitudinal Studies
Male
Middle Aged
Saliva
Saliva - chemistry
Salivation - physiology
Taste
Taste Disorders - metabolism
Taste Disorders - physiopathology
Xerostomia
Xerostomia - metabolism
Xerostomia - physiopathology
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Summary:The aim of this study was to investigate the relationships between oral sensorial complaints (OSCs) and salivary flow rate, composition and drug consumption of subjects aged 18–90 years. The results were correlated with both drug consumption and OSCs. Only individuals who were free of conditions that are already known to cause OSCs were included in the study. The three most significant observations were as follows: (1) elderly people have significantly reduced and altered salivary secretion compared with younger people. While specific concentrations increased, the total values of most salivary components decreased in the elderly; (2) 50% of the elderly population have OSCs regarding taste, burning mouth syndrome or xerostomia; and (3) OSCs were more prevalent in elderly people who use drugs than in those who do not. In conclusion, a reduction in salivary function and altered composition are age related. A compensatory capacity that prevents OSCs appears to exist in elderly patients who do not use drugs, but drugs were found to have an extensive effect on OSCs. The finding that the total amounts of salivary components and not only the salivary flow rate were reduced in elderly people is of great clinical relevance, since such a reduction is expected to be reflected in compromising various salivary functions.
ISSN:0003-9969
1879-1506
DOI:10.1016/j.archoralbio.2004.07.012