Blood pressure and vessel recanalization in the first hours after ischemic stroke

Transient elevation of arterial blood pressure (BP) is frequent in acute ischemic stroke and may help to increase perfusion of tissue jeopardized by ischemia. If this is true, recanalization may eliminate the need for this BP elevation. We analyzed BP in 149 patients with acute ischemic stroke on ad...

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Bibliographic Details
Published in:Stroke (1970) 2005-02, Vol.36 (2), p.264-268
Main Authors: Mattle, Heinrich P, Kappeler, Liliane, Arnold, Marcel, Fischer, Urs, Nedeltchev, Krassen, Remonda, Luca, Jakob, Stephan M, Schroth, Gerhard
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Analysis of Variance
Animals
Antihypertensive Agents - pharmacology
Blood Pressure
Blood Pressure Determination
Brain Ischemia - diagnosis
Brain Ischemia - pathology
Brain Ischemia - therapy
Cerebral Arteries - pathology
Cerebrovascular Disorders - diagnosis
Diastole
Humans
Middle Aged
Myocardial Infarction - pathology
Perfusion
Stroke - diagnosis
Stroke - pathology
Stroke - therapy
Systole
Thrombolytic Therapy - methods
Time Factors
Treatment Outcome
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Summary:Transient elevation of arterial blood pressure (BP) is frequent in acute ischemic stroke and may help to increase perfusion of tissue jeopardized by ischemia. If this is true, recanalization may eliminate the need for this BP elevation. We analyzed BP in 149 patients with acute ischemic stroke on admission to the hospital and 1 and 12 hours after intraarterial thrombolysis. BP values of patients with adequate recanalization were compared with BP values of patients with inadequate recanalization. Recanalization was determined on cerebral arteriography after thrombolysis using thrombolysis in myocardial infarction grades. Systolic, mean, and diastolic arterial BP decreased significantly from admission to 12 hours after thrombolysis in all patients (P
ISSN:0039-2499
1524-4628
DOI:10.1161/01.STR.0000153052.59113.89