Cardiac Ventricular Diastolic and Systolic Duration in Children With Heart Failure Secondary to Idiopathic Dilated Cardiomyopathy

Systole and diastole are the fundamental periods of the cardiac cycle, yet little emphasis has been placed on their relative duration when evaluating heart failure. Cardiac intervals are used to assess ventricular function, but the relative duration of systole and diastole for defining function have...

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Bibliographic Details
Published in:The American journal of cardiology 2006, Vol.97 (1), p.101-105
Main Authors: Friedberg, Mark K., Silverman, Norman H.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Blood Flow Velocity - physiology
Blood pressure
Cardiology
Cardiology. Vascular system
Cardiomyopathy, Dilated - complications
Cardiomyopathy, Dilated - physiopathology
Case-Control Studies
Child
Child, Preschool
Children & youth
Diastole - physiology
Echocardiography, Doppler
Female
Heart
Heart failure
Heart Failure - etiology
Heart Failure - physiopathology
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Heart Rate - physiology
Humans
Infant
Linear Models
Male
Medical sciences
Mitral Valve Insufficiency - diagnostic imaging
Mitral Valve Insufficiency - physiopathology
Myocarditis. Cardiomyopathies
Retrospective Studies
Systole - physiology
Tricuspid Valve Insufficiency - diagnostic imaging
Tricuspid Valve Insufficiency - physiopathology
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Description
Summary:Systole and diastole are the fundamental periods of the cardiac cycle, yet little emphasis has been placed on their relative duration when evaluating heart failure. Cardiac intervals are used to assess ventricular function, but the relative duration of systole and diastole for defining function have not been evaluated. We hypothesized that in heart failure, systole is prolonged and diastole shortened. We defined systole and diastole in 16 children with idiopathic dilated cardiomyopathy and in 16 normal controls, matched for age and gender, using the mitral regurgitant (MR) and tricuspid regurgitant (TR) flow duration. The systole and diastole durations (expressed as a fraction of the cardiac cycle) were correlated with heart rate and age and compared between groups. The subjects were compared with gender- and age-matched controls (9.98 ± 6.1 vs 9.88 ± 6.08 years, p = NS). The 2 groups had similar heart rates (104 ± 31 vs 92 ± 34 beats/min, p = NS). The systole duration was not significantly different when measured by MR versus TR duration (0.60 ± 0.10 vs 0.57 ± 0.11 of the cardiac cycle, respectively, p = NS). Systole was prolonged in subjects compared with controls (0.60 ± 0.1 vs 0.42 ± 0.08, respectively, using MR duration, p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2005.07.127